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Cytokeratin 7 & CDX2 (EP16 & EP25), RMab
SKU: |
BSB 6653 |
Antibody type:
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Rabbit Monoclonal
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Clone:
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EP16 & EP25
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Isotype:
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IgG
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Concentrate Dilution:
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1:25-1:100
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Localization:
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Cytoplasmic, Nuclear
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Tissue Control:
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Colon, Breast, Ovary, Lung Carcinoma
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Species Reactivity:
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Human
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Cytokeratin 7 (CK7) reacts with proteins that are found in most ductal, glandular and transitional epithelium of the urinary tract and bile duct epithelial cells. CK7 distinguishes between lung and breast epithelium that stain positive, and colon and prostate epithelial cells that are negative. CDX2 is a caudal-type homeobox gene that encodes an intestine-specific transcription factor expressed early in intestinal development and that may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells.
The Cytokeratin 7 antibody has been shown to label the rete epithelium in the testis, epididymis epithelium, and the surface epithelium of the stomach and duodenum. Transitional-cell Carcinomas are positive and Prostate Cancers are negative. CDX2 antibody has been useful in distinguishing the gastrointestinal origin of Metastatic Adenocarcinomas and Carcinoids. A high percentage of Mucinous Carcinomas of the Ovary also stain positively with this antibody, as well as Carcinomas from the upper gastrointestinal tract.
Presentation
Cytokeratin 7 & CDX2 antibody is a rabbit monoclonal cocktail antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: keratin 7, KRT7, sc23876, sc-23876, 23876, anti-Cytokeratin 7, anti Cytokeratin 7, anti-KRT7, anti KRT7, anti-Keratin 7, anti Keratin 7, CK 7, CK7, cytokeratin 7, K2C7, K7, keratin 55K type II cytoskeletal, keratin simple epithelial type I K7, keratin type II cytoskeletal 7, MGC129731, MGC3625, Sarcolectin, SCL, type II mesothelial keratin K7, D15Wsu77e, keratin complex 2 basic gene 7, Krt2 7, MGC11625, Cytokeratin 18, CK 18, Keratin 18, K18, Type II keratin Kb7, anti-ck7, anti ck7, anti-ck 7, CDX3, sc393572, sc-393572, 393572, CDX2, anti-Cdx2, anti Cdx2, CDX-2, anti-CDX-2, anti CDX-2, anti-CDX3, anti CDX3, caudal type homeobox 2, CDX 3, CDX2 AS
Specification Sheets
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Option | SKU | Price |
Presentation: 3 ml Predilute | BSB 6653 | $354.90 |
Presentation: 7 ml Predilute | BSB 6654 | $641.55 |
Presentation: 15 ml Predilute | BSB 6655 | $1,124.55 |
Presentation: .1 ml Concentrate | BSB 6656 | $260.40 |
Presentation: .5 ml Concentrate | BSB 6657 | $562.80 |
Presentation: 1 ml Concentrate | BSB 6658 | $1,042.65 |
Presentation: Control Slides [5] | BSB-9150-CS | $67.00 |
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