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HLA-DRB1 beta chain (EP191), RMab
| SKU: |
BSB 2433 |
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Antibody type:
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Rabbit Monoclonal
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Clone:
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EP191
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Isotype:
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IgG
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Concentrate Dilution:
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1:25-1:100
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Localization:
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Cytoplasmic
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Tissue Control:
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Tonsil, Spleen, Liver, Kidney, Adrenal
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Species Reactivity:
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Human
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
HLA class II histocompatibility antigen, DRB1-9 beta chain belongs to the HLA class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. HLA-DRB1 antibody is expressed mainly on antigen-presenting cells, such as B lymphocytes, monyctes and dendritic cells, but can also be detected on activated T lymphocytes and activated granulocytes.
In abnormal tissues, HLA-DRB1 antibody expression has been found in different types of Acute Lymphoblastic Leukemias and Acute Myeloid Leukemias. Additionally, HDLADR was also found in some nonhematopoietic tumors, including carcinomas of the colon and breast.
Presentation
HLA-DRB1 Beta Chain antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: HLA-DRβ, HLA-DRbeta, HLA-DR beta, HLA-DRb, HLA-DR b, HLA DR beta, sc-53314, 53314, HLA DRβ, HLADRβ, HLA-DRB1, DRB1, DW2 2 DR2 2, FLJ76359, HLA class II histocompatibility antigen DR 1 beta chain, HLA class II histocompatibility antigen DRB1 15 beta chain, HLA DR1B, HLA DRB, HLA DRB1, human leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex class II DR beta 1, MHC class II HLA DR beta 1 chain, MHC class II HLA DR beta cell surface glycoprotein, SS1, DR beta 5, DR2 beta 2, DRw10, dw2, FLJ75017, HLA class II histocompatibility antigen DR 5 beta chain, HLA class II histocompatibility antigen DRB1 10 beta chain, HLA DRB5, human leucocyte antigen DRB5, leukocyte antigen class II, major histocompatibility complex class II DR beta 5, MHC class II HLA beta chain, MHC class II HLA DRw10 beta, MHC HLA DR beta cell surface glycoprotein, MHC HLA DR beta chain, Clone P2 beta 3, DR 1, DR 5, DR 8, DR 9, DR1, DR5, DR8, DR9, DRw11, DRw8, HLA class II histocompatibility antigen DR beta 5 chain, HLA class II histocompatibility antigen DRB1 1 beta chain, HLA class II histocompatibility antigen DRB1 11 beta chain, HLA class II histocompatibility antigen DRB1 3 chain, HLA class II histocompatibility antigen DRB1 8 beta chain, HLA class II histocompatibility antigen DRB1 9 beta chain, MHC class II antigen DRB1 10, MHC class II antigen DRB1 11, MHC class II antigen DRB1 3, MHC class II antigen DRB1 9, MHC class II antigen DRB1 1, MHC class II antigen DRB1 15, MHC class II antigen DRB1 8, MHC class II antigen DRB5, MHC class II antigen
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 2433 | $266.00 |
| Presentation: 7 ml Predilute | BSB 2434 | $483.00 |
| Presentation: 15 ml Predilute | BSB 2435 | $870.00 |
| Presentation: .1 ml Concentrate | BSB 2436 | $189.00 |
| Presentation: .5 ml Concentrate | BSB 2437 | $423.00 |
| Presentation: 1 ml Concentrate | BSB 2438 | $786.00 |
| Presentation: Control Slides [5] | BSB 2439 | $63.00 |
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