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Lambda (Polyclonal), RPab
SKU: |
BSB 3092 |
Antibody type:
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Rabbit Polyclonal
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Clone:
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Polyclonal
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Isotype:
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IgG
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Concentrate Dilution:
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1:500 / 1:10
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Localization:
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Cytoplasmatic
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Tissue Control:
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Tonsil, Lymph Node
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Species Reactivity:
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Human
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Intended Use
For In Vitro Diagnostic Use.
This antibody is intended for use in Immunohistochemical (IHC) and Immunofluorescence (IF) applications on formalin-fixed paraffin-embedded tissues (FFPE), frozen tissue sections and cell preperations. Interpretation of results should be perfomed by a qualified medical professional.
Summary and Explanation
Lambda antibody detects surface immunoglobulin on normal and neoplastic B-cells. Lambda staining is seen in B-cell follicles of human lymphoid tissue.
When studying B-cell neoplasms, the determination of light chain ratios remains the centerpiece. This is sound reasoning because most B-cell Lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda-positive cells. If only a single light-chain type is detected, a lymphoproliferative disorder is very likely. Monoclonality is determined by a kappa-lambda ratio greater than or equal to 3:1, a lambda-kappa ratio greater than or equal to 2:1, or a monoclonal population of 75% or more of the total population. In IgG-dominant immune complex-mediated glomerulonephritis, there are multiple pathological findings that strongly suggest the diagnosis of Lupus Nephritis including immunofluorescence staining for IgG, IgM, IgA, Kappa or Lambda, C3 and C1.
Presentation
Lambda antibody is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: IGLL1, immunoglobulin lambda like polypeptide 1, 14 1, AGM2, CD179b, IGL1, IGL5, IGLJ14 1, IGLL, IGO, IGVPB, VPREB2, anti-lambda, anti lambda, igll, anti-igll, anti igll
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Option | SKU | Price |
Presentation: 3 ml Predilute | BSB 3092 | $97.65 |
Presentation: 7 ml Predilute | BSB 3093 | $163.80 |
Presentation: 15 ml Predilute | BSB 3094 | $288.75 |
Presentation: .1 ml Concentrate | BSB 3095 | $103.95 |
Presentation: .5 ml Concentrate | BSB 3096 | $195.30 |
Presentation: 1 ml Concentrate | BSB 3097 | $275.10 |
Presentation: Control Slides [5] | BSB 3689 | $63.00 |
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