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PMS2 (BSB-130), MMab

Presentation:

Price: $657.00

SKU:	BSB-2373-15
Antibody type:	Mouse Monoclonal
Clone:	BSB-130
Isotype:	lgG1
Concentrate Dilution:	1:25-1:100
Localization:	Nuclear
Tissue Control:	Breast, Skin, Cervix, Salivary Gland
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

PMS2 is a gene that encodes for DNA repair proteins involved in mismatch repair. Carriers of the mismatch repair gene mutations have a high lifetime risk of developing Hereditary Non-Polyposis Colon Cancer (HNPCC) and several other cancers including endometrial cancer due to microsatellite instability (MSI) caused by accumulation of DNA replication errors in proliferating cells.

Along with MLH1, MSH2 and MSH6, PMS2 is helpful in diagnosing MSI. Tumors with low-level MSI show unfavorable pathological characteristics compared to tumors with none and tumors with high-level MSI.

Presentation

Anti-PMS2 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Prediluted	BSB-2373-3	$226.00
Presentation: 7 ml Prediluted	BSB-2373-7	$411.00
Presentation: 15 ml Prediluted	BSB-2373-15	$657.00
Presentation: .1 ml Concentrated	BSB-2373-01	$161.00
Presentation: .5 ml Concentrated	BSB-2373-05	$360.00
Presentation: 1 ml Concentrated	BSB-2373-05	$668.00
Presentation: Control Slides [5]	BSB-2373-CS	$63.00

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PMS2 (BSB-130), MMab

Intended Use

Summary and Explanation

Presentation

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