AMACRacemase / P504S (13H4), RMab
AMACRacemase / P504S (13H4), RMab
Price:
$239.00
SKU:
BSB 5057
Antibody type:
Rabbit Monoclonal
Clone:
13H4
Isotype:
IgG
Concentrate Dilution:
1:25-1:100
Localization:
Cytoplasmic
Tissue Control:
Kidney, Liver, Salivary Gland, Prostate Lesions, P
Species Reactivity:
Human
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Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
AMACR (P504S) is an acronym for the protein alpha-methylacyl CoA racemase that helps to metabolize certain fatty acids within the body. AMACR has been recently described as a prostate cancer-specifi c gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in Prostatic Adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of the prostate: High-Grade Prostatic Intraepithelial Neoplasia (PIN) and Atypical Adenomatous Hyperplasia. Several studies have suggested that AMACR can be used as a prostate cancer biomarker.
High expression of AMACR antibody (P504S) protein is usually found in Prostatic Adenocarcinoma but not in benign prostatic tissue by immunohistochemical staining in paraffin-embedded tissues. Using AMACR as a positive marker along with basal-cell staining (34βE12 or p63) as a negative marker could help to confirm the diagnosis of small foci of Prostate Carcinoma on needle biopsies.
Presentation
AMACRacemase antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: AMACR, 2 methylacyl CoA racemase, alpha methylacyl CoA racemase, CBAS4, RACE, RM, AMACRD, amacr, alpha-methylacyl coa racemase, anti-amacr, anti-alpha-methylacyl
Documentation
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 5057 | $239.00 |
| Presentation: 7 ml Predilute | BSB 5058 | $397.00 |
| Presentation: 15 ml Predilute | BSB 5059 | $716.00 |
| Presentation: .1 ml Concentrate | BSB 5060 | $245.00 |
| Presentation: .5 ml Concentrate | BSB 5061 | $559.00 |
| Presentation: 1 ml Concentrate | BSB 5062 | $851.00 |
| Presentation: Control Slides [5] | BSB-9013-CS | $101.00 |
