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Androgen Receptor (BSB-4), MMab

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Price: $162.00

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SKU: BSB 6071

Antibody type: Mouse Monoclonal

Clone: BSB-4

Isotype: IgG1

Concentrate Dilution: 1:100-1:500

Localization: Nuclear

Tissue Control: Prostate, Testis, Breast, Cervix

Species Reactivity: Human

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Description

Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

The androgen receptor (AR) is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone. The main function of the androgen receptor is as a DNA-binding transcription factor which regulates gene expression. However, the androgen receptor has additional functions independent of DNA binding. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and the brain.

Androgen Receptor antibody reacts with the androgen receptor and also with the newly-described A form of the receptor. This antibody does not cross-react with estrogen, progesterone or glucocorticoid receptors. Abnormalities in the AR-signaling pathway have been linked to a number of diseases, including Prostate Cancer, Kennedy’s Disease and male infertility.

Presentation

Androgen receptor antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: anti-androgen receptor, ar antibody, anti-ar, ar ihc, androgen-receptor, anti-androgen-receptor, anti androgen receptor

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Specification Sheets

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Safety Data Sheets

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Product Details

Option	SKU	Price
Presentation: 3 ml Predilute	BSB 6071	$162.00
Presentation: 7 ml Predilute	BSB 6072	$293.00
Presentation: 15 ml Predilute	BSB 6073	$529.00
Presentation: .1 ml Concentrate	BSB 6074	$160.00
Presentation: .5 ml Concentrate	BSB 6075	$403.00
Presentation: 1 ml Concentrate	BSB 6076	$767.00
Presentation: Control Slides [5]	BSB-9016-CS	$101.00

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