bcl-2 (EP36), RMab
Price:
$283.00
SKU:
BSB 6541
Antibody type:
Rabbit Monoclonal
Clone:
EP36
Isotype:
IgG
Concentrate Dilution:
1:50-1:200
Localization:
Cytoplasmic, Membranous
Tissue Control:
Tonsil, Lymph Node, Breast, Placenta
Species Reactivity:
Human, Predicted: Mouse
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
bcl-2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of bcl-2, such as in the case of translocation of bcl-2 to Ig heavy-chain loci, is thought to be the cause of Follicular Lymphoma.
The bcl-2 antibody has shown consistent negative reaction on reactive germinal centers and positive staining of neoplastic follicles in Follicular Lymphoma. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. This antibody may also be used in distinguishing between those Follicular Lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2-negative. The bcl-2 antibody has been used as a predictive biomarker for recurrence of Cancer of the Breast and Non-Small- Cell Carcinoma of the lung.
Presentation
bcl-2 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: ARG1, arginase liver, arginase 1, Liver type arginase, type I arginase, anti-arginase, anti-arginase-1, anti arg1, anri-arg1, anti-arg
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 6541 | $283.00 |
| Presentation: 7 ml Predilute | BSB 6542 | $511.00 |
| Presentation: 15 ml Predilute | BSB 6543 | $918.00 |
| Presentation: .1 ml Concentrate | BSB 6544 | $314.00 |
| Presentation: .5 ml Concentrate | BSB 6545 | $691.00 |
| Presentation: 1 ml Concentrate | BSB 6546 | $1,054.00 |
| Presentation: Control Slides [5] | BSB-9029-CS | $101.00 |
