Intended Use
For In Vitro Diagnostic Use.
This antibodyis intended for use in Immunohistochemical applications on formalin-fixed paraffin-embedded tissues (FFPE), frozen tissue sections and cell preparations. Interpretation of results should be performed by a qualified medical professional.
Summary and Explanation
Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell
proliferation, differentiation and neoplastic disease. A mutated version of
MYC is found in manycancers,which causes Myc to be constitutively
expressed. This leads to the unregulated expression of many genes,
some of which are involved in cell proliferation, and results in the
formation of cancer.c-Myc is a transcription factor and is a
proto-oncogene that is the focal point in cell cycle regulation,
metabolism, apoptosis, differentiation,cell adhesion, and tumorigenesis.
A common human translocation involving Myc is t(8; 14) which is critical
to the development of most cases of Burkitt’s Lymphoma.Malfunctions in
Myc have also been found in carcinoma of the cervix,colon, breast, lung,
and stomach.
Presentation
Anti-c-Myc is a Rabbit Monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5,containing BSA and sodium azide as a preservative.
Synonyms: c Myc, MYC, cMyc, sc40, sc-40, 40, anti-c-Myc, anti c-Myc, anti-c Myc, anti-cMyc, anti c Myc, anti cMyc, anti-Myc, anti Myc, avian myelocytomatosis viral oncogene homolog, bHLHe39, Myc proto oncogene protein, transcription factor p64, v myc avian myelocytomatosis viral oncogene homolog, v myc myelocytomatosis viral oncogene homolog avian, class E basic helix loop helix protein 39, MRTL, myc related translation localization regulatory factor, Proto oncogene c Myc, 9E10
