Caldesmon (BSB-19), MMab
Price:
$162.00
SKU:
BSB 6099
Antibody type:
Mouse Monoclonal
Clone:
BSB-19
Isotype:
IgG1/K
Concentrate Dilution:
1:100-1:400
Localization:
Cytoplasmic
Tissue Control:
Appendix, Uterus, Breast Ducts
Species Reactivity:
Human
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Caldesmon antibody 1, also known as CALD1, is a human gene. Caldesmon is a calmodulin-binding protein. Like Calponin, Caldesmon tonically inhibits the ATPase activity of myosin in smooth muscle. This gene encodes a Calmodulin and actin-binding protein that play an essential role in the regulation of smooth muscle and nonmuscle contraction.
Two closely-related variants of human Caldesmon have been identified. The h-Caldesmon variant (120–150 kD) is predominantly expressed in smooth muscle, whereas I-Caldesmon (70–80 kD) is found in non-muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. Caldesmon antibody recognizes only the h-Caldesmon variant. Caldesmon antibody labels smooth muscle and tumors of smooth muscle, myofibroblastic, and myoepithelial differentiation. Anti-Caldesmon has also been used to differenti-ate Epithelioid Mesothelioma from Serous Papillary Carcinoma of the ovary.
Presentation
Caldesmon antibody (CALD-31) is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: caldesmon bsb-19, anti-cald-1, anti-caldesmon 1,anti-caldesmon-1, CALD1, L Caldesmon, LCaldesmon, Caldesmon, caldesmon 1, CDM, H CAD, L CAD, MGC21352, NAG22, HCAD, LCAD
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 6099 | $162.00 |
| Presentation: 7 ml Predilute | BSB 6100 | $278.00 |
| Presentation: 15 ml Predilute | BSB 6101 | $529.00 |
| Presentation: .1 ml Concentrate | BSB 6102 | $127.00 |
| Presentation: .5 ml Concentrate | BSB 6103 | $484.00 |
| Presentation: 1 ml Concentrate | BSB 6104 | $668.00 |
| Presentation: Control Slides [5] | BSB-9052-CS | $101.00 |
