Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Calretinin is a vitamin D-dependent calcium-binding protein involved in calcium signaling. It is expressed in the central and peripheral nervous system and in many normal and pathological tissues. It stains Mesothelioma and can be used to help differentiate lung tumors. Calretinin antibody is also considered an important diagnostic tool in the differential diagnosis of cystic and solid Ameloblastic Tumors.
Calretinin antibody has been shown to be useful in differentiating Mesothelioma from Adenocarcinomas of the lung and other sources. It is also useful in differentiating adrenal-cortical neoplasms from Pheochromocytomas.
Presentation
Calretinin antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: CALB2, 29 kDa calbindin, CAB29, CAL2, calbindin 2, calbindin 2 29kD calretinin, calbindin D29K, calretinin, CR, anti-cr, anti-calretinin,,anti-cal1, anti-calbindin