Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
CD11c antibody (1TGAX) is a member of the leukointegrin family and shares the same beta subunit with other members of the leukocyte adhesion molecule family, which include CD11a (LFA-1), CD11b (MAC-1), and CD11d (ITGAD), but has a unique alpha chain. CD11c is a type I transmembrane protien found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst.
CD11c antibody is expressed in Hairy Cell leukemias, Acute Nonlymphocytic Leukemias, and some B-cell Chronic Lymphocytic Leukemias.
Presentation
Cd11c antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: Cd11c, Integrin αX, Integrin alphaX, Integrin alpha X, Integrin α X, Itgax, anti-Integrin αX, anti Integrin αX, anti-Itgax, anti Itgax, Integrin alpha-X, anti-CD11C, anti CD11C, anti-Integrin alpha-X, anti Integrin alpha-X, AI449405, Cr4, N418, CD11C p150, complement receptor 4, integrin aX