Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
CD138/Syndecan-1 is a transmembrane heparin-sulphate proteoglycan which is made up of one core protein and five glycosaminoglycans. CD138 is expected to play a role in cell adhesion. It is expressed on the surface of pre B-cells and plasma cells but is absent from mature B-cells.
Anti-CD138/syndecan-1 is a useful marker for labeling normal and neoplastic plasma cells and Plasmacytoid Lymphomas. It is a selective marker for B-cell Lymphoblastic Leukemia and Lymphoplasmacytoid Leukemia. It is lost from the apoptotic myeloma cells, and thus, is a useful marker for viable Myeloma cells. Various forms of Hodgkin’s Disease have also shown positive staining with this antibody.
Presentation
CD138 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: Syndecan 1, CD138, SYND1, sc390791, Syndecan1, SDC1, anti-Syndecan-1, anti Syndecan-1, anti-SDC1, anti SDC1, anti-Syndecan 1, anti-Syndecan1, anti Syndecan 1, anti Syndecan1, anti-CD138, anti CD138, anti-SYND1, anti SYND1, SDC, syndecan