Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
CD31 is also called PECAM-1 for platelet endothelial cell-adhesion molecule. It plays a key role in removing aged neutrophils from the body. CD31 is normally found on stem cells, endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T/NK cells, lymphocytes, megakaryocytes, fibroblasts, osteoclasts and neutrophils. CD31 antibody is also expressed in certain tumors, including Epithelioid Hemangioendothelioma, Epithelioid Sarcoma-like Hemangioendothelioma, other vascular tumors, Histiocytic malignancies, and Plasmacytomas. It is rarely found in some sarcomas and carcinomas. CD31 and macrophages play a key role in tissue regeneration.
CD31 antibody is widely used to identify the vascular origin of neoplasms, as it is a highly specific and sensitive marker for vascular endothelial cells.
Presentation
CD31 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: Cd31, PECAM 1, PECAM1, sc376764, sc-376764, 376764, anti CD31, anti endoCAM, anti PECAM 1, anti PECAM-1, anti PECAM1, anti-CD31, anti-endoCAM, anti-PECAM 1, anti-PECAM-1, anti-PECAM1, endoCAM, PECAM-1, C85791, MGC102160, Pecam, PECAM 1 CD31, Platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule 1, anti-cd31, anti cd31
