CD33 (RBT-CD33), RMab
Price:
$331.00
SKU:
BSB 3448
Antibody type:
Rabbit Monoclonal
Clone:
RBT-CD33
Isotype:
IgG
Concentrate Dilution:
1:10-1:50
Localization:
Membranous
Tissue Control:
Placenta, Myometrium, Lung, Colon
Species Reactivity:
Human
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Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
CD33 (gp62 or siglec-3) is a glycosylated transmembrane protein that is a member of the sialic acid-binding immunoglobulin-like lectin (siglec) family. The genomic locus of this protein has been mapped to chromosome 19q13.1-3.5. The function of CD33 is not known, but it may have a role in cell-to-cell adhesion. In maturing granulocytic cells, there is progressive down-regulation of CD33 from the blast stage to mature neutrophils. However, in monocytes and macrophages/histiocytes, strong expression of CD33 is maintained throughout maturation.
Detection of CD33 using monoclonal antibodies has been a critical component in immunophenotyping acute leukemias, particularly Acute Myeloid Leukemias.
Presentation
CD33 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: CD33 antigen gp67, CD33 molecule, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig like lectin 3, Siglec 3, SIGLEC3, anti-cd33, anti cd33
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 3448 | $331.00 |
| Presentation: 7 ml Predilute | BSB 3449 | $603.00 |
| Presentation: 15 ml Predilute | BSB 3450 | $1,081.00 |
| Presentation: .1 ml Concentrate | BSB 3451 | $363.00 |
| Presentation: .5 ml Concentrate | BSB 3452 | $977.00 |
| Presentation: 1 ml Concentrate | BSB 3453 | $1,477.00 |
| Presentation: Control Slides [5] | BSB-9086-CS | $101.00 |
