Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
CD5 is a glycoprotein monomer with an MW of 67 kDa belonging to the scavenger receptor cysteine-rich (SRCR) family of extracellular domain-like structures, and it possesses a large cytoplasmic domain suitable for signal transduction.
CD5 antibody is a T-cell marker that also reacts with a range of neoplastic B-cells, e.g., B-cell Chronic Lymphocytic Leukemia (B-CLL), B-cell Small Lymphocytic Lymphoma (B-SLL), and Mantle Cell Lymphoma. CD5 expression is found in T-lymphocyte subsets and is modulated during cellular activation; however, it does not react with granulocytes or monocytes.
Presentation
CD5 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: CD5, anti-cd5, anti cd5, CD5 antigen p56 62, CD5 molecule, LEU1, Lymphocyte antigen T1 Leu 1, T cell surface glycoprotein CD5, T1