CD74 (LN2), MMab
Price:
$124.00
SKU:
BSB 5295
Antibody type:
Mouse Monoclonal
Clone:
LN2
Isotype:
IgG1
Concentrate Dilution:
1:250-1:1000
Localization:
Cytoplasmic, Membranous
Tissue Control:
Tonsil, Lymph Node
Species Reactivity:
Human
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
CD74, also known as the MHC Class II-associated invariant chain (II), is a Type II transmembrane protein which binds to the peptide-binding groove of newly-synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen-presenting cells such as B-lymphocytes (from before the pre-B-cell stage to before the plasma-cell stage), macrophages and monocytes, together with many epithelial cells.
CD74 antibody stains predominantly germinal-center lymphocytes and B-cell lymphomas but rarely T-cell lymphomas. It stains the cell membrane but a paranuclear globular labeling is also noted. CD74 antibody is useful in differentiating Atypical Fibroxanthoma from Malignant Fibrous Histiocytoma, as well as Small-cell Lung Carcinoma from Non-small cell Lung Carcinomas.
Presentation
CD74 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: CD74, HLA class II histocompatibility antigen gamma chain, anti-CD74, anti CD74, anti-HLA class II histocompatibility antigen gamma chain, anti HLA class II histocompatibility antigen gamma chain, CD74 antigen invariant polypeptide of major histocompatibility complex class II antigen associated, CD74 molecule major histocompatibility complex class II invariant chain, DHLAG, gamma chain of class II antigens, HLA DR antigens associated invariant chain, HLA DR gamma, HLADG, Ia antigen associated invariant chain, Ia associated invariant chain, Ia GAMMA, Ii, MHC HLA DR gamma chain, p33, FLJ98970
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 5295 | $124.00 |
| Presentation: 7 ml Predilute | BSB 5296 | $201.00 |
| Presentation: 15 ml Predilute | BSB 5297 | $388.00 |
| Presentation: .1 ml Concentrate | BSB 5298 | $152.00 |
| Presentation: .5 ml Concentrate | BSB 5299 | $278.00 |
| Presentation: 1 ml Concentrate | BSB 5300 | $445.00 |
| Presentation: Control Slides [5] | BSB 5301 | $77.05 |
