CDX2 (EP25), RMab
Price:
$365.00
SKU:
BSB 6057
Antibody type:
Rabbit Monoclonal
Clone:
EP25
Isotype:
IgG
Concentrate Dilution:
1:50-1:200
Localization:
Nuclear
Tissue Control:
Colon, Colon Adenocarcinoma
Species Reactivity:
Human, Predicted: Rabbit
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
CDX2 is a rabbit monoclonal antibody for immunohistochemistry from Bio SB. CDX2 is a caudal-type homeobox gene that encodes an intestine-specific transcription factor expressed early in intestinal development and that may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum.
The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demon-strated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer. It is not expressed in the normal gastric mucosa. Loss of CDX2 protein expression has been correlated with loss of differentiation in colorectal cancers. The CDX2 antibody has been useful in distinguishing the gastrointestinal origin of metastatic adenocarcinomas and carcinoids. Studies have shown that the CDX2 antibody is a superior marker compared to CK20. A high percentage of mucinous carcinomas of the ovary also stain positively with this antibody, as well as Carcinomas from the upper gastrointestinal tract.
Presentation
CDX2 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: cdx2, cd-x2. cdx-2, anti-cdx2, anti cdx2, caudal type homeobox 2, CDX 3, CDX2 AS, CDX3
Documentation
Specification Sheets
Safety Data Sheets
Ask a Question
There are currently no questions about this
product.
Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 6057 | $365.00 |
| Presentation: 7 ml Predilute | BSB 6058 | $524.00 |
| Presentation: 15 ml Predilute | BSB 6059 | $1,034.00 |
| Presentation: .1 ml Concentrate | BSB 6060 | $238.00 |
| Presentation: .5 ml Concentrate | BSB 6061 | $711.00 |
| Presentation: 1 ml Concentrate | BSB 6062 | $1,069.00 |
| Presentation: Control Slides [5] | BSB-9116-CS | $101.00 |
