Claudin-5 (EP224), RMab
Price:
$269.00
SKU:
BSB 2398
Antibody type:
Rabbit Monoclonal
Clone:
EP224
Isotype:
IgG
Concentrate Dilution:
1:25-1:100
Localization:
Cytoplasmic, Membranous
Tissue Control:
Liver, Vascular Tissue, Placenta
Species Reactivity:
Human
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Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Claudin-5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction (TJ) strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Claudin-5 is an endothelial cell-specific component of TJ strands. Mutations in Claudin-5 have been found in patients with velocardiofacial syndrome.
Claudin-5 antibody labels endothelial cells and has been used as a marker for endothelial lesions. Claudin-5 is also found in bronchial and lung epithelial cells. In tumors, Claudin-5 expression has been found in lung adenocarcinoma and squamous carcinoma. In serous ovarian adenocarcinoma, increased Claudin-5 expression is associated with aggressive behavior.
Presentation
Claudin-5 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: Claudin 5, CLDN5, claudin5, anti-claudin-5, anti claudin-5, anti-CLDN5, anti CLDN5, anti-claudin 5, anti-claudin5, anti claudin 5, anti claudin5, AWAL, BEC1, CPETRL1, TMDVCF, TMVCF, Transmembrane protein deleted in VCFS, transmembrane protein deleted in velocardiofacial syndrome
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 2398 | $269.00 |
| Presentation: 7 ml Predilute | BSB 2399 | $482.00 |
| Presentation: 15 ml Predilute | BSB 2400 | $877.00 |
| Presentation: .1 ml Concentrate | BSB 2401 | $299.00 |
| Presentation: .5 ml Concentrate | BSB 2402 | $657.00 |
| Presentation: 1 ml Concentrate | BSB 2403 | $1,005.00 |
| Presentation: Control Slides [5] | BSB-9120-CS | $101.00 |
