Collagen Type IV (CIV22), MMab
Collagen Type IV (CIV22), MMab
Price:
$174.00
SKU:
BSB 5351
Antibody type:
Mouse Monoclonal
Clone:
CIV22
Isotype:
IgG1/K
Concentrate Dilution:
1:50-1:200
Localization:
Cytoplasmic
Tissue Control:
Muscle, Lung
Species Reactivity:
Human, Rat,Canine, Horse
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% of the total protein content. Collagen IV is a major constituent of the basement membranes, along with laminins and enactins. It is composed of the alpha 1 IV chain and alpha 2 IV chain in a 2:1 ratio. It can form insoluble fibers with high tensile strength.
Normal tissue stains with this antibody in a manner consistent with the sites of mesenchymal elements and epithelial basal laminae. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas. Collagen IV can also be useful in the classification of soft tissue tumors; Schwanomas, Leiomyomas, and their well-differentiated malignant counterparts usually immunoreact to this antibody. The vascular nature of neoplasms, Hemangiopericytoma, Angiosarcoma and Epithelioid Hemangioendothelioma can be observed with this antibody.
Presentation
Collagen Type IV antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Special Note: Collagen Type IV antibody requires the use of ImmunoDNA Digestor (Cat.#’s BSB 0108, BSB 0109, BSB 0110, BSB 0111, BSB 0112) or similar Proteinase K based product as antigen retriever.
Synonyms: collagen type 4, COL4A1, anti-collagen type iv, anti collagen type 4, COL4A6, procollagen type IV alpha 6
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 5351 | $174.00 |
| Presentation: 7 ml Predilute | BSB 5352 | $314.00 |
| Presentation: 15 ml Predilute | BSB 5353 | $561.00 |
| Presentation: .1 ml Concentrate | BSB 5354 | $152.00 |
| Presentation: .5 ml Concentrate | BSB 5355 | $323.00 |
| Presentation: 1 ml Concentrate | BSB 5356 | $562.00 |
| Presentation: Control Slides [5] | BSB-9123-CS | $101.00 |
