Cyclin B1 (RM281), RMab
Price:
$210.00
SKU:
BSB-3760-3
Antibody type:
Rabbit Monoclonal
Clone:
RM281
Isotype:
IgG
Concentrate Dilution:
1:100-1:500
Localization:
Cytoplasmic
Tissue Control:
Testis, Breast, Colon, Cervix
Species Reactivity:
Human
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Cyclin B1 is a regulatory protein involved with mitosis. It complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Cyclin B1 contributes to the switch-like all or none behavior of the cell in deciding to commit mitosis. Its activation is well regulated, and positive feedback loops ensure that once the cyclin B1-Cdk1 complex is activated it is not deactivated. Cyclin B1-Cdk1 is involved in the early events of mitosis, such as chromosome condensation, nuclear envelope breakdown, and spindle pole assembly. Before mitosis almost all cyclin B1 in the cell is located in the cytoplasm, but in late prophase it relocates to the nucleus. At the end of mitosis, cyclin B1 is targeted for degradation by the APC through its APC localization sequence, permitting the cell to exit mitosis.
Cyclin B1 antibody overexpression has been detected in various tumor types.
Presentation
Cyclin B1 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: CCNB1, anti-cyclin B1, anti cyclin B1, anti-CCNB1, anti CCNB1, CCNB, cyclin B1, G2 mitotic specific cyclin B1
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB-3760-3 | $210.00 |
| Presentation: 7 ml Predilute | BSB-3760-7 | $380.00 |
| Presentation: 15 ml Predilute | BSB-3760-15 | $683.00 |
| Presentation: .1 ml Concentrate | BSB-3760-01 | $233.00 |
| Presentation: .5 ml Concentrate | BSB-3760-05 | $513.00 |
| Presentation: 1 ml Concentrate | BSB-3760-1 | $781.00 |
| Presentation: Control Slides [5] | BSB-9129-CS | $101.00 |
