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Cyclin D3 (BSB-171), MMab

cd3, anti cd3, anti-cd3, CCND3, anti-cyclin D3, anti cyclin D3, anti CCND3, anti-CCND3, cyclin D3 MAIN

Cyclin D3 (BSB-171), MMab

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Price: $225.00

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SKU: BSB-3799-3

Antibody type: Mouse Monoclonal

Clone: BSB-171

Isotype: IgG1

Concentrate Dilution: 1:25-1:100

Localization: Nuclear

Tissue Control: Adrenal Gland, Transitional Cell Carcinoma, Testis

Species Reactivity: Human

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Description

Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Cyclin D3 is a protein that in humans is encoded by the CCND3 gene. Cyclin D3 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, required for the G1/S cell cycle phase transition. Abnormal expression of Cyclin D3 was found in many different cancers and may be an unfavorable prognostic biomarker for various malignancy patients.

Expression of Cyclin D3 was significantly associated with breast cancer prognosis and was shown to be an independent prognostic marker in breast cancer; high Cyclin D3 expression indicates poor disease free survival rate in breast cancer. Increased p27 expression in Hurthle Cell variant of Follicular Thyroid Carcinoma was shown to be caused by the overexpression of Cyclin D3. Cyclin D3 overexpression also plays a role in the progression of Pancreatic Adenocarcinoma as well as androgen receptor-dependent proliferation in Prostatic Adenocarcinoma.

Synonyms: cd3, anti cd3, anti-cd3, CCND3, anti-cyclin D3, anti cyclin D3, anti CCND3, anti-CCND3, cyclin D3

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Specification Sheets

IVD - CE

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Product Details

Option	SKU	Price
Presentation: 3 ml Predilute	BSB-3799-3	$225.00
Presentation: 7 ml Predilute	BSB-3799-7	$337.00
Presentation: 15 ml Predilute	BSB-3799-15	$564.00
Presentation: .1 ml Concentrate	BSB-3799-01	$225.00
Presentation: .5 ml Concentrate	BSB-3799-05	$451.00
Presentation: 1 ml Concentrate	BSB-3799-1	$788.00
Presentation: Control Slides [5]	BSB-9437-CS	$101.00

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