Cytokeratin 14 (LL002), MMab
Cytokeratin 14 (LL002), MMab
Price:
$142.00
SKU:
BSB 6219
Antibody type:
Mouse Monoclonal
Clone:
LL002
Isotype:
IgG3
Concentrate Dilution:
1:50-1:200
Localization:
Cytoplasmic
Tissue Control:
Squamous Mucosa, Prostate, Breast
Species Reactivity:
Human, Rats
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Cytokeratin 14 is a Type I polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. It is usually found as a heterotetramer with two cytokeratin 5 molecules, and a Type II keratin. Together, they form the cytoskeleton of epithelial cells. Mutations in the genes for these cytokeratins are associated with Epidermolysis Bullosa Simplex.
Cytokeratin 14 antibody has been studied as a prognostic marker in Breast Cancer. This antibody labels the basal layer of stratifying squamous and non-squamous epithelia. The staining pattern is cytoplasmic. It recognizes Basal Cell Carcinomas and Squamous Cell Carcinomas. Cytokeratin 14 antibody has been demonstrated to be useful in differentiating Squamous Cell Carcinomas from other epithelial tumors. This antibody has also been useful in separating oncocytic tumors of the kidney from renal mimics, as well as in determining metaplastic Carcinomas of the Breast.
Presentation
Cytokeratin 14 antibody (CK14 antibody) is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: keratin 14, KRT14, anti-Cytokeratin 14, anti Cytokeratin 14, anti-KRT14, anti KRT14, anti-Keratin 14, anti Keratin 14, CK 14, CK14, anti-ck14, anti ck14, anti-ck 14, cytokeratin 14, EBS3, EBS4, K14, keratin 14 epidermolysis bullosa simplex Dowling Meara Koebner, Keratin type I cytoskeletal 14, NFJ
Documentation
Specification Sheets
Safety Data Sheets
Ask a Question
There are currently no questions about this
product.
Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 6219 | $142.00 |
| Presentation: 7 ml Predilute | BSB 6220 | $211.00 |
| Presentation: 15 ml Predilute | BSB 6221 | $372.00 |
| Presentation: .1 ml Concentrate | BSB 6222 | $133.00 |
| Presentation: .5 ml Concentrate | BSB 6223 | $251.00 |
| Presentation: 1 ml Concentrate | BSB 6224 | $458.00 |
| Presentation: Control Slides [5] | BSB-9134-CS | $101.00 |
