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FGFR-3 (BSB-150), MMab

fgfr-3, fgfr 3, fgfr3, anti-fgfr-3, anti-fgfr 3, anti-fgfr3, fibroblast growth actor receptor 3, anti- fibroblast growth MAIN

FGFR-3 (BSB-150), MMab

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Price: $227.00

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SKU: BSB-3724-3

Antibody type: Mouse Monoclonal

Clone: BSB-150

Isotype: IgG2a

Concentrate Dilution: 1:25-1:100

Localization: Cytoplasmic, Membranous

Tissue Control: Skin, Liver, Brain, Testis, TCC

Species Reactivity: Human

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Description

Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

The FGFR3 gene encodes the protein Fibroblast Growth Factor Receptor 3 (FGFR3), part of a family of four fibroblast growth factor receptors that share similar structures and functions. These proteins play a role in several important cellular processes, including regulation of cell growth and proliferation, determination of cell type, angiogenesis, wound healing, and embryo development.

Approximately 80% of Non-Muscle Invasive Bladder Cancer (NMIBC) tumors have FGFR3 gene mutations. In addition to high prevalence in Bladder Cancer, somatic mutations in the FGFR3 gene have been associated with Multiple Myeloma and Cervical Cancer. FGFR3 gene aberrations have also been reported in Urothelial, Breast, Head/Neck, Lung, Brain, Gastric, Pancreatic, Colorectal, Kidney, Endometrial, Ovarian, and Cervical Cancers. FGFR-3 antibody, which is highly expressed in Cutaneous Malignant Melanoma (CMM) tissues, is correlated with increased Breslow thickness and lymph node metastasis.

Presentation

FGFR-3 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: fgfr-3, fgfr 3, fgfr3, anti-fgfr-3, anti-fgfr 3, anti-fgfr3, fibroblast growth actor receptor 3, anti- fibroblast growth factor receptor 3

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Product Details

Option	SKU	Price
Presentation: 3 ml Predilute	BSB-3724-3	$227.00
Presentation: 7 ml Predilute	BSB-3724-7	$408.00
Presentation: 15 ml Predilute	BSB-3724-15	$717.00
Presentation: .1 ml Concentrate	BSB-3724-01	$236.00
Presentation: .5 ml Concentrate	BSB-3724-05	$515.00
Presentation: 1 ml Concentrate	BSB-3724-1	$848.00
Presentation: Control Slides [5]	BSB-9178-CS	$101.00

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