FOXP1 (EP137), RMab
Price:
$243.00
SKU:
BSB 6751
Antibody type:
Rabbit Monoclonal
Clone:
EP137
Isotype:
IgG
Concentrate Dilution:
1:25-1:100
Localization:
Nuclear, Cytoplasmic
Tissue Control:
Tonsil, Lymph Node, Breast
Species Reactivity:
Human, Predicted: Mouse, Rat
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
FOXP1 is part of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in regulation of tissue- and cell-type specific gene transcription during both development and adulthood. The FOXP1 protein contains both DNA-binding- and protein-protein binding-domains. FOXP1 is a transcriptional repressor and is responsible for regulating a variety of important aspects of development including tissue development of the lungs, brain, thymus and heart. It is also important in muscle development of the esophagus and esophageal epithelium and for regulating lung airway morphogenesis.
Strong expression of FOXP1 antibody is associated with poor disease-free survival and transformation to Diffuse Large B-cell Lymphomas. Recently, studies suggested a role of FOXP1 in the regulation of ER expression. FOXP1 expression is correlated with ER expression and improved survival in breast cancer patients. Nuclear expression of FOXP1 is associated with ER expression, while cytoplasmic expression of FOXP1 is linked to myometrial invasion in endometrial cancer.
Presentation
FOXP1 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: FOXP1, anti-foxp1, anti foxp1, fork head related protein like B, forkhead box P1, Forkhead box protein P1, glutamine rich factor 1, hFKH1B, HSPC215, MGC12942, MGC88572, MGC99551, QRF1
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 6751 | $243.00 |
| Presentation: 7 ml Predilute | BSB 6752 | $439.00 |
| Presentation: 15 ml Predilute | BSB 6753 | $790.00 |
| Presentation: .1 ml Concentrate | BSB 6754 | $282.00 |
| Presentation: .5 ml Concentrate | BSB 6755 | $624.00 |
| Presentation: 1 ml Concentrate | BSB 6756 | $962.00 |
| Presentation: Control Slides [5] | BSB-9185-CS | $101.00 |
