FOXP3 (EP340), RMab
Price:
$306.00
SKU:
BSB 2922
Antibody type:
Rabbit Monoclonal
Clone:
EP340
Isotype:
IgG
Concentrate Dilution:
1:25-1:100
Localization:
Nuclear
Tissue Control:
Tonsil, Lymph Node, Thymus, Colon
Species Reactivity:
Human
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
FOXP3, also known as scurfin, is a protein involved in immune system responses. A member of the forkhead box protein family, FOXP3 appears to function as a transcription factor in the development and function of regulatory T cells. In regulatory T cell model systems, the FOXP3 transcription factor occupies the promoters of many important for regulatory T-cell function, and may repress transcription of key genes following stimulation of T cell receptors.
Alterations in numbers of regulatory T-cells – in particular those that express FOXP3 antibody – are found in a number of disease states. Patients with tumors have a local relative excess of FOXP3 positive T cells which inhibits the body’s ability to suppress the formation of cancerous cells.
Presentation
FOXP3 antibody s a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: FOXP3, anti-FOXP3, anti FOXP3, forkhead box P3 (FOXP3), anti-forkhead box P3 (FOXP3), anti forkhead box P3 (FOXP3), forkhead/winged-helix transcription regulator family member FOXP3 (forkhead box P3), X-linked syndrome (IPEX) related, anti-forkhead/winged-helix transcription regulator family member FOXP3 (forkhead box P3), anti forkhead/winged-helix transcription regulator family member FOXP3 (forkhead box P3), anti-X-linked syndrome (IPEX) related, anti X-linked syndrome (IPEX) related, AIID, DIETER, forkhead box P3, Forkhead box protein P3, immune dysregulation polyendocrinopathy enteropathy X linked, immunodeficiency polyendocrinopathy enteropathy X linked, IPEX, JM2, MGC141961, MGC141963, PIDX, Scurfin, XPID, FOXP3delta7, foxp
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 2922 | $306.00 |
| Presentation: 7 ml Predilute | BSB 2923 | $460.00 |
| Presentation: 15 ml Predilute | BSB 2924 | $767.00 |
| Presentation: .1 ml Concentrate | BSB 2925 | $306.00 |
| Presentation: .5 ml Concentrate | BSB 2926 | $638.00 |
| Presentation: 1 ml Concentrate | BSB 2927 | $1,116.00 |
| Presentation: Control Slides [5] | BSB-9186-CS | $101.00 |
