Granzyme B (EP230), RMab
Price:
$214.00
SKU:
BSB 2405
Antibody type:
Rabbit Monoclonal
Clone:
EP230
Isotype:
IgG
Concentrate Dilution:
1:25-1:100
Localization:
Cytoplasmic (Granular)
Tissue Control:
Liver, Testis, Cervix, Tonsil, Lymph Node
Species Reactivity:
Human
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Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Granzymes are exogenous serine proteases that are released by cytoplasmic granules within cytotoxic T-cells and natural killer cells. Their purpose is to induce apoptosis within virus-infected cells, thus destroying them.
Granzyme B antibody has been useful in diagnosing Natural Killer/T-cell Lymphoma, as well as Anaplastic Large Cell Lymphoma. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin’s Disease.
Presentation
Granzyme B antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: anti-granzyme b, anti granzyme b, anti-gb, anti gb, GZMB, granzyme B granzyme 2 cytotoxic T lymphocyte associated serine esterase 1, CCPI, CGL 1, CGL1, CSP B, CSPB, CTLA1, CTSGL1, HLP, SECT
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 2405 | $214.00 |
| Presentation: 7 ml Predilute | BSB 2406 | $388.00 |
| Presentation: 15 ml Predilute | BSB 2407 | $700.00 |
| Presentation: .1 ml Concentrate | BSB 2408 | $238.00 |
| Presentation: .5 ml Concentrate | BSB 2409 | $524.00 |
| Presentation: 1 ml Concentrate | BSB 2410 | $799.00 |
| Presentation: Control Slides [5] | BSB-9201-CS | $101.00 |
