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IFN-y (BSB-161), MMab

IGN-y, IFNy, IFN y, anti-ifn-y, anti-ifny, anti-ifn y, gamma, ifn-gamma, ifn gamma, anti-ifn-gamma, IGN-y, IFNy, IFN y, MAIN

IFN-y (BSB-161), MMab

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Price: $217.00

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SKU: BSB-3734-3

Antibody type: Mouse Monoclonal

Clone: BSB-161

Isotype: IgG2a

Concentrate Dilution: 1:50-1:200

Localization: Cytoplasmic, Membranous

Tissue Control: Stomach, Falopian Tube, Colon

Species Reactivity: Human

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Description

Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

IFN-γ is a dimerized soluble cytokine and the only member of the type II interferon. In humans, IFN-γ is encoded by the IFNG gene and is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. IFN-γ is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocytes effector T cells once antigen-specific immunity develops as part of the adaptive immune response. IFN-γ is also produced by non-cytotoxic innate lymphoid cells.

IFN-γ interacts with its receptors interferon gamma receptor 1 and interferon gamma receptor 2 and activates them. IFN-γ binding to the receptors activates the JAK-STAT pathway. IFN-γ also binds to the glycosaminoglycan heparan sulfate and inhibits its biological activity. IFN-γ is used to treat Chronic Granulomatous Disease and Osteopetrosis, also has potential as cancer immunotherapy to improve survival in Bladder Carcinoma, Melanoma, and Ovarian Carcinoma.

Synonyms: IGN-y, IFNy, IFN y, anti-ifn-y, anti-ifny, anti-ifn y, gamma, ifn-gamma, ifn gamma, anti-ifn-gamma

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Product Details

Option	SKU	Price
Presentation: 3 ml Predilute	BSB-3734-3	$217.00
Presentation: 7 ml Predilute	BSB-3734-7	$389.00
Presentation: 15 ml Predilute	BSB-3734-15	$684.00
Presentation: .1 ml Concentrate	BSB-3734-01	$226.00
Presentation: .5 ml Concentrate	BSB-3734-05	$491.00
Presentation: 1 ml Concentrate	BSB-3734-1	$779.00
Presentation: Control Slides [5]	BSB-9232-CS	$101.00

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IFN-y (BSB-161), MMab

IFN-y (BSB-161), MMab

Description

Intended Use

Summary and Explanation

Documentation

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Product Details

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