IgM (BSB-41), MMab
Price:
$100.00
SKU:
BSB 5680
Antibody type:
Mouse Monoclonal
Clone:
BSB-41
Isotype:
IgG1/K
Concentrate Dilution:
1:100-1:500
Localization:
Cytoplasmic
Tissue Control:
Tonsil, Lymph Node, Spleen, Kidney, Colon
Species Reactivity:
Human
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
IgM forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, normally as a pentamer or occasionally as a hexamer. It has a large molecular mass of approximately 900 kDa (in its pentamer form). In germline cells, the gene segment encoding the constant region of the heavy chain is positioned first among other constant region gene segments. For this reason, IgM is the first immunoglobulin expressed by mature B-cells.
IgM antibody reacts with surface immunoglobulin IgM mu chains. IgM is one of the predominant surface immunoglobulins on B-lymphocytes, and is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived Hodgkin’s Lymphomas. Due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell Lymphomas is possible with clonal gene-rearrangement studies.
Presentation
IgM antibody is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: IGHM, anti-igm, anti igm, AGM1, DKFZp686I15196, DKFZp686I15212, FLJ00385, Ig mu chain C region, immunoglobulin heavy constant mu, MGC104996, MGC52291, MU, VH
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 5680 | $100.00 |
| Presentation: 7 ml Predilute | BSB 5681 | $162.00 |
| Presentation: 15 ml Predilute | BSB 5682 | $291.00 |
| Presentation: .1 ml Concentrate | BSB 5683 | $127.00 |
| Presentation: .5 ml Concentrate | BSB 5684 | $162.00 |
| Presentation: 1 ml Concentrate | BSB 5685 | $227.00 |
| Presentation: Control Slides [5] | BSB-9238-CS | $101.00 |
