Islet 1 / ISL1 (EP283), RMab
Islet 1 / ISL1 (EP283), RMab
Price:
$291.00
SKU:
BSB 2971
Antibody type:
Rabbit Monoclonal
Clone:
EP283
Isotype:
IgG
Concentrate Dilution:
1:25-1:100
Localization:
Nuclear
Tissue Control:
Pancreas, Testis, Thyroid, Cervix
Species Reactivity:
Human
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Islet-1, Insulin gene enhancer protein ISL-1, is a protein that in humans is encoded by the ISL1 gene. This gene encodes a transcription factor containing two N-terminal LIM domains and one C-terminal homeo domain. The encoded protein plays an important role in the embryogenesis of pancreatic islets of Langerhans. ISL1 has been shown to interact with Estrogen Receptor alpha.
Islet-1 antibody produces a strong nuclear staining in the islets of normal pancreas and tumor cells of the pancreatic neuroendocrine tumors. Islet-1 has been found to be a reliable marker of pancreatic endocrine tumors and metastasis. It shows a comparable sensitivity and specificity as CDX2 as a marker of ileal and appendiceal neuroendocrine tumors and their metastasis. TTF1 is very rarely expressed in well-differentiated gastroentero-pancreatic endocrine tumors. Therefore, the panel of Islet-1 CDX2, and TTF1 and they may be useful for examining metastasis of well-differentiated endocrine carcinomas of unknown origin.
Presentation
Islet-1 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: Islet1, Islet 1, ISL1, ISL LIM homeobox 1, Isl 1, anti-islet-1, anti islet-1, anti-isl1, anti isl1, anti-islet 1, anti islet 1
Documentation
Specification Sheets
Safety Data Sheets
Ask a Question
There are currently no questions about this
product.
Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 2971 | $291.00 |
| Presentation: 7 ml Predilute | BSB 2972 | $439.00 |
| Presentation: 15 ml Predilute | BSB 2973 | $732.00 |
| Presentation: .1 ml Concentrate | BSB 2974 | $291.00 |
| Presentation: .5 ml Concentrate | BSB 2975 | $587.00 |
| Presentation: 1 ml Concentrate | BSB 2976 | $1,024.00 |
| Presentation: Control Slides [5] | BSB-9248-CS | $101.00 |
