Kappa Light Chains (BSB-58), MMab
Kappa Light Chains (BSB-58), MMab
Price:
$119.00
SKU:
BSB 5701
Antibody type:
Mouse Monoclonal
Clone:
BSB-58
Isotype:
IgG1/K
Concentrate Dilution:
1:250-1:1000
Localization:
Cytoplasmic
Tissue Control:
Tonsil, Lymph Node
Species Reactivity:
Human, Dog, Cat
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Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Kappa detects surface immunoglobulin on normal and neoplastic B-cells. In paraffin-embedded tissue, Kappa exhibits strong staining of kappa-positive plasma cells and cells that have absorbed exogenous immunoglobulin.
When studying B-cell neoplasms, the determination of light-chain ratios remains the centerpiece. This is sound reasoning because most B-cell Lymphomas express either the kappa light chains antibody or the lambda light chains antibody, whereas reactive proliferations display a mixture of kappa and lambda-positive cells. If only a single light-chain type is detected, a lympho-proliferative disorder is very likely. Monoclonality is determined by a kappa-lambda ratio greater than or equal to 3:1, a lambda-kappa ratio greater than or equal to 2:1, or a monoclonal population of 75% or more of the total population.
Presentation
Kappa antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: Ig κ chain, Ig kappa chain, IGKC, immunoglobulin kappa constant, HCAK1, IGKCD, Km, anti-Kappa Light Chains, anti Kappa Light Chains, anti-klc, anti klc
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 5701 | $119.00 |
| Presentation: 7 ml Predilute | BSB 5702 | $201.00 |
| Presentation: 15 ml Predilute | BSB 5703 | $356.00 |
| Presentation: .1 ml Concentrate | BSB 5704 | $127.00 |
| Presentation: .5 ml Concentrate | BSB 5705 | $239.00 |
| Presentation: 1 ml Concentrate | BSB 5706 | $339.00 |
| Presentation: Control Slides [5] | BSB-9250-CS | $101.00 |
