Mammaglobin (EP249), RMab
Mammaglobin (EP249), RMab
Price:
$289.00
SKU:
BSB 5743
Antibody type:
Rabbit Monoclonal
Clone:
EP249
Isotype:
IgG
Concentrate Dilution:
1:25-1:100
Localization:
Cytoplasmic
Tissue Control:
Breast, Skin, Fallopian Tube, Breast Carcinoma
Species Reactivity:
Human, Mouse, Monkey, Predicted: Rat
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Mammaglobin is a gene that encodes a 10 kDa glycoprotein. In humans, expression of the gene is limited to the adult mammary gland. A correlation between increased expression of the gene and Breast Cancer has been reported. Mammaglobin mRNA is present in high levels in human Breast Cancer cell lines and primary Breast Cancers. High levels of mRNA have been detected in normal human sweat glands as well, but are absent in Sweat Gland Tumors.
Mammaglobin Antibody (EP249) has been shown to be effective in detecting up to 85% of Breast Carcinomas using immunohistochemical techniques. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of Breast Cancer patients have shown that mammaglobin is a highly-specific marker and correlates with several prognostic factors, such as lymph node involvement.
Presentation
Mammaglobin antibody (31A5) is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: secretoglobin family 2A member 2, MGB1, UGB2, anti-mammaglobin, anti mammaglobin
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 5743 | $289.00 |
| Presentation: 7 ml Predilute | BSB 5744 | $527.00 |
| Presentation: 15 ml Predilute | BSB 5745 | $894.00 |
| Presentation: .1 ml Concentrate | BSB 5746 | $238.00 |
| Presentation: .5 ml Concentrate | BSB 5747 | $524.00 |
| Presentation: 1 ml Concentrate | BSB 5748 | $841.00 |
| Presentation: Control Slides [5] | BSB-9265-CS | $101.00 |
