MCM3 (EP202), RMab
Price:
$353.00
SKU:
BSB 6884
Antibody type:
Rabbit Monoclonal
Clone:
EP202
Isotype:
IgG
Concentrate Dilution:
1:25-1:100
Localization:
Nuclear
Tissue Control:
Colon Carcinoma
Species Reactivity:
Human, Predicted: Mouse, Rat
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication proteins. MCM3 is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progrsession.
Increased expression of MCM3 antibody has been demonstrated in various tymors by immunohistochemistry and is used as a marker for tumor progression.
Presentation
MCM3 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: MCM3, anti-MCM3, anti MCM3, minichromosome maintenance complex component 3, HCC5, P1 MCM3, P1 h, RLFB, mcm-3, anti-mcm-3, anti mcm-3
Documentation
Specification Sheets
Safety Data Sheets
Ask a Question
There are currently no questions about this
product.
Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 6884 | $353.00 |
| Presentation: 7 ml Predilute | BSB 6885 | $639.00 |
| Presentation: 15 ml Predilute | BSB 6886 | $1,024.00 |
| Presentation: .1 ml Concentrate | BSB 6887 | $260.00 |
| Presentation: .5 ml Concentrate | BSB 6888 | $592.00 |
| Presentation: 1 ml Concentrate | BSB 6889 | $1,081.00 |
| Presentation: Control Slides [5] | BSB 6890 | $77.05 |
