Mesothelin (EP140), RMab
Price:
$196.00
SKU:
BSB 6919
Antibody type:
Rabbit Monoclonal
Clone:
EP140
Isotype:
IgG
Concentrate Dilution:
1:50-1:200
Localization:
Cytoplasmic, Membranous, Nuclear
Tissue Control:
Cervix, Tonsil, Mesothelioma, Ovarian Cancer
Species Reactivity:
Human, Dog, Cat
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Mesothelin was first identified by its reactivity with monoclonal antibody K1. The mesothelin gene encodes a precursor protein that is processed to yield mesothelin, which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-KDa shed fragment named megakaryocyte-potentiating factor (MPF). Its biological function is not known, but recent studies have shown that mesothelin forms a strong and specific complex with MUC16, which has been suggested to be the basis of ovarian cancer metastasis.
Mesothelin antibody expression is present on normal mesothelial cells lining the pleura, peritoneum, and pericardium. In tumors, overexpression of Mesothelin has been observed in mesotheliomas, and other tumors including ovarian, pancreatic carcinomas, and cholangiocarcinoma.
Presentation
Mesothelin antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: Msln, megakaryocyte potentiating factor, Mesothelin, Mesothelin cleaved form, MPF, Pre pro megakaryocyte potentiating factor, anti-mesothelin, anti mesothelin
Documentation
Specification Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 6919 | $196.00 |
| Presentation: 7 ml Predilute | BSB 6920 | $357.00 |
| Presentation: 15 ml Predilute | BSB 6921 | $639.00 |
| Presentation: .1 ml Concentrate | BSB 6922 | $219.00 |
| Presentation: .5 ml Concentrate | BSB 6923 | $482.00 |
| Presentation: 1 ml Concentrate | BSB 6924 | $734.00 |
| Presentation: Control Slides [5] | BSB 6925 | $77.05 |
