MSH6 (44), MMab
Price:
$162.00
SKU:
BSB 6142
Antibody type:
Mouse Monoclonal
Clone:
44
Isotype:
IgG1
Concentrate Dilution:
1:50-1:200
Localization:
Nuclear
Tissue Control:
Colon Mucosa, Colon Carcinoma
Species Reactivity:
Human, Rat, Mouse, Dog
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
MSH6 is mouse monoclonal antibody (MMab) for immunohistochemistry from Bio SB. MSH6 is a gene commonly associated with Hereditary Non-Polyposis Colorectal Cancer (HNPCC). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset Colorectal Carcinoma and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited Colorectal Cancer in the western world. MSH6 is a mismatch repair gene which is deficient in a high proportion of patients with microsatellite instability (MSI-H).
The MSH6 antibody is useful in screening patients and families for HNPCC. Colon cancers that are microsatellite-unstable have a better prognosis than their microsatellite-stable counterparts.
Presentation
MSH6 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: msh-6, anti msh6, anti-msh6, anti msh-6, gtbp, anti-gdbp, SH6, DNA mismatch repair protein Msh6, G T mismatch binding protein, GTBP, GTMBP, HNPCC5, HSAP, mutS homolog 6 E coli, MutS alpha 160 kDa subunit, p160, sperm associated protein, hMSH6
Documentation
Specification Sheets
Safety Data Sheets
Ask a Question
There are currently no questions about this
product.
Product Details
Option | SKU | Price |
Presentation: 3 ml Predilute | BSB 6142 | $162.00 |
Presentation: 7 ml Predilute | BSB 6143 | $293.00 |
Presentation: 15 ml Predilute | BSB 6144 | $530.00 |
Presentation: .1 ml Concentrate | BSB 6145 | $198.00 |
Presentation: .5 ml Concentrate | BSB 6146 | $484.00 |
Presentation: 1 ml Concentrate | BSB 6147 | $788.00 |
Presentation: Control Slides [5] | BSB-9285-CS | $101.00 |