MUM1 (EP190), RMab
                    
                    
                    
                        
                        
				
                            
					
    
            
						
                
            
					
            
						
                
            
					
        
    
				 
                        
			 
                        
                        
				
                            Price:
                            $336.00
                        
			
                        
                     
                    
                    
                    
                    
				
                        SKU:
                        BSB 6953
                    
			
                    
        
				
            Antibody type:
            Rabbit Monoclonal
        
			
    
        
				
            Clone:
            EP190
        
			
    
        
				
            Isotype:
            IgG
        
			
    
        
				
            Concentrate Dilution:
            1:25-1:100
        
			
    
        
				
            Localization:
            Cytoplasmic, Nuclear
        
			
    
        
				
            Tissue Control:
            Tonsil, Spleen, Colon, Kidney
        
			
    
        
				
            Species Reactivity:
            Human, Canine, Feline
        
			
    
                    
				
    
					
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        Description
        
						
            Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
MUM1 (multiple myeloma oncogene-1) also known as interferon regulatory factor 4 (IRF4) is a 50 kDa protein and is a member of the interferon regulatory factor family of transcription factors. It is induced by antigen receptor mediated stimuli and plays an important role in cell proliferation, differentation and survival. MUM1 antibody is expressed in the nuclei and cytoplasm of plasma cells and a small percentage of germinal center (GC) B-cells commited to plasmacytic or memory cell differentation in the “light zone”.
MUM1 is useful for subclassification of lymphoid malignancies and is an excellent marker for Hodgkin’s and Reed-Sternberg cells of classic Hodgin’s disease.
Presentation
MUM1 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: MUM1, melanoma associated antigen mutated 1, EXPAND1, HSPC211, MUM 1, mum-1, anti-mum1, anti-mum-1, anti mum1, anti mum-1
 
    
				 
    
					
        Documentation
        
						Specification Sheets
Safety Data Sheets
					 
    
				 
    
    
					
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											| Option | SKU | Price | 
											| Presentation: 3 ml Predilute | BSB 6953 | $336.00 | 
											| Presentation: 7 ml Predilute | BSB 6954 | $610.00 | 
											| Presentation: 15 ml Predilute | BSB 6955 | $996.00 | 
											| Presentation: .1 ml Concentrate | BSB 6956 | $248.00 | 
											| Presentation: .5 ml Concentrate | BSB 6957 | $556.00 | 
											| Presentation: 1 ml Concentrate | BSB 6958 | $1,033.00 | 
											| Presentation: Control Slides [5] | BSB-9292-CS | $101.00 |