Back

NUT/NUTM1 (RBT-NUTM1), RMab

nut, anti-nut, anti nut, nutm1, anti-nutm1, anti nutm1, nuclear protein in testis Nut MAIN

NUT/NUTM1 (RBT-NUTM1), RMab

Presentation:

Price: $225.00

Quantity:

Add To Cart

SKU: BSB-3793-3

Antibody type: Rabbit Monoclonal

Clone: RBT-NUTM1

Isotype: IgG

Concentrate Dilution: 1:50-1:200

Localization: Nuclear

Tissue Control: Testis

Species Reactivity: Human

Sharing Discount has been applied

Description

Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Nuclear protein in Testis (NUT or NUTM1) is a nuclear protein encoded by the NUTM1 gene on Chromosome 15 and normally expressed in testicular tissues. NUT is an unstructured protein with few orthologs, and shuttles between the nucleus and cytoplasm. NUT Cancer (formerly NUT Midline Carcinoma) occurs after a gene fusion event between NUTM1 and often a bromodomain (BRD) family gene in ~75% of cases. NUTM1 less commonly fuses with NSD3, MXD4, MGA, ZNF532, CIC, and other rare variants, which are all considered to be NUT cancers.

NUT cancers can be carcinomas, sarcomas, lymphomas, and other types of tumors, and are often formed in the head, neck, or mediastinum. However, primary cancers have been reported in kidney, bladder, lung, breast, and metastasis to lymph nodes has also been seen for these very aggressive tumors. NUT cancers generally have poorly differentiated morphology with sudden transitions to well-differentiated squamous epithelium. The cells express high molecular weight cytokeratins and p63 or p40, although the presence of NUTM1 antibody confirms the identity of the tumor.

Synonyms: nut, anti-nut, anti nut, nutm1, anti-nutm1, anti nutm1, nuclear protein in testis Nut

Documentation

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

Ask a Question

There are currently no questions about this product.

New

Product Details

Option	SKU	Price
Presentation: 3 ml Predilute	BSB-3793-3	$225.00
Presentation: 7 ml Predilute	BSB-3793-7	$337.00
Presentation: 15 ml Predilute	BSB-3793-15	$564.00
Presentation: .1 ml Concentrate	BSB-3793-01	$225.00
Presentation: .5 ml Concentrate	BSB-3793-05	$451.00
Presentation: 1 ml Concentrate	BSB-3793-1	$788.00

Returning Customer? Log In | My Account

(805) 692-2768 | sales@biosb.com

Use Non-Mobile Version

Back Check Out

Enter Coupon Calculate Shipping

Privacy Policy Shipping Policy Return Policy

Back

Ask Question: NUT/NUTM1 (RBT-NUTM1), RMab

Please ask a question about the product NUT/NUTM1 (RBT-NUTM1), RMab.

Your First Name:

Your Last Name:

Your E-Mail Address:

Your E-Mail Address: (Re-type to confirm)

Your Question:

Submit Cancel

Submit Question: NUT/NUTM1 (RBT-NUTM1), RMab

Thank you for your question about the product NUT/NUTM1 (RBT-NUTM1), RMab.

Back

In Stock Notification

First Name:

Last Name:

Notify me when the NUT/NUTM1 (RBT-NUTM1), RMab is in stock.

Submit Cancel

Close

Back

In Stock Notification

First Name:

Last Name:

Notify me when the NUT/NUTM1 (RBT-NUTM1), RMab is in stock.

Submit Cancel

Close