p120 Catenin (EP66), RMab
    
			
		 
                
                
			
                    p120 Catenin (EP66), RMab
                    
                    
                    
                        
                        
				
                            
					
    
            
						
                
            
					
            
						
                
            
					
        
    
				 
                        
			 
                        
                        
				
                            Price:
                            $336.00
                        
			
                        
                     
                    
                    
                    
                    
				
                        SKU:
                        BSB 2077
                    
			
                    
        
				
            Antibody type:
            Rabbit Monoclonal
        
			
    
        
				
            Clone:
            EP66
        
			
    
        
				
            Isotype:
            IgG
        
			
    
        
				
            Concentrate Dilution:
            1:100-1:500
        
			
    
        
				
            Localization:
            Cytoplasmic, Membranous
        
			
    
        
				
            Tissue Control:
            Breast, Testis, Kidney, Prostate
        
			
    
        
				
            Species Reactivity:
            Human, Predicted: Mouse, Rat, Rabbit
        
			
    
                    
				
    
					
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        Description
        
						
            Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
p120 Catenin antibody is a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be important for cadherins cell-adhesion properties. Cytoplasmic accumulation of p120 Catenin has been observed in lung cancer, pancreatic cancer, gastric cancer and colon cancers and is associated with poor prognosis in colon cancer patients.
In breast lobular neoplasia, p120 Catenin antibody shows a diffuse cytoplasmic immunostaining pattern, while breast ductal neoplasia retains the membrane immunostaining pattern. p120 Catenin can be useful in differentiating between lobular carcinoma and ductal carcinoma of the breast, and in identifying early lesions of lobular neoplasia.
Presentation
p120 antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: Ctnnd1, Cadherin associated Src substrate, CAS, catenin cadherin associated protein delta 1, Catenin delta 1, catenin src, Catns, Ctnnd, mKIAA0384, P120, p120 catenin, p120 cas, p120 ctn, anti-p120, anti p120, anti-catenin, anti catenin,
 
    
				 
    
					
        Documentation
        
						Specification Sheets
Safety Data Sheets
					 
    
				 
    
    
					
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											| Option | SKU | Price | 
											| Presentation: 3 ml Predilute | BSB 2077 | $336.00 | 
											| Presentation: 7 ml Predilute | BSB 2078 | $610.00 | 
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