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pTau Phospho (Thr 181) (BSB-176), MMab

p Tau, phospho Tau, phosphorylated Tau, p- Tau, pTau, anti p Tau, anti p-Tau, anti pTau MAIN

pTau Phospho (Thr 181) (BSB-176), MMab

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Price: $225.00

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SKU: BSB-3807-3

Antibody type: Mouse Monoclonal

Clone: BSB-176

Isotype: IgG1κ

Concentrate Dilution: 1:25-1:50

Localization: Cytoplasmic, Perinuclear

Tissue Control: Brain

Species Reactivity: Human

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Description

Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Tau is a phosphorylated protein, containing 85 potential serine (S), threonine (T), and tyrosine (Y) phosphorylation sites. Both the phosphorylation status and isoform expression of tau are developmentally regulated and both are important factors for cytoskeletal plasticity during embryogenesis and early development. Despite the significant heterogeneity that exists between and within the various tauopathies, the deposited tau in pathological lesions is invariably highly phosphorylated.

Characteristic accumulations of highly phosphorylated tau protein (Thr 181) aggregates are found in several neurodegenerative tauopathies including Alzheimer’s Disease (AD), Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD), and some forms of Frontotemporal Lobar Dementia (FTLD-tau).

Synonyms: p Tau, phospho Tau, phosphorylated Tau, p- Tau, pTau, anti p Tau, anti p-Tau, anti pTau

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Specification Sheets

IVD - CE

Safety Data Sheets

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Product Details

Option	SKU	Price
Presentation: 3 ml Predilute	BSB-3807-3	$225.00
Presentation: 7 ml Predilute	BSB-3807-7	$337.00
Presentation: 15 ml Predilute	BSB-3807-15	$564.00
Presentation: .1 ml Concentrate	BSB-3807-01	$225.00
Presentation: .5 ml Concentrate	BSB-3807-05	$451.00
Presentation: 1 ml Concentrate	BSB-3807-1	$788.00
Presentation: Control Slides [5]	BSB-9445-CS	$101.00

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