Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Transcription factor SOX-11 is a member of the group C SOX (SRY-related HMG-box) transcription factor family involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis and adult neurogenesis. SOX-11 antibody is normally expressed in the developing human central nervous system, Medulloblastoma, and Glioma.
SOX-11 antibody nuclear protein expression is highly associated with both Cyclin D1-positive and negative Mantle Cell Lymphomas, with a stronger and more homogeneous Immunohistochemistry staining than Cyclin D1.
Presentation
SOX-11 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: sox-11, sox 11, sox11, anti-sox-11, anti-sox 11, anti-sox11, anti sox-11, anti sox 11, anti sox11