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TLE1 (RBT-TLE1), RMab

TLE1, anti-TLE1, anti TLE1, Enhancer of split groucho-like protein 1 (ESG1), Tle4l MAIN

TLE1 (RBT-TLE1), RMab

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Price: $225.00

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SKU: BSB-3794-3

Antibody type: Rabbit Monoclonal

Clone: RBT-TLE1

Isotype: IgG

Concentrate Dilution: 1:50-1:200

Localization: Cytoplasmic, Nuclear

Tissue Control: Synovial Sarcoma

Species Reactivity: Human

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Description

Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

The Notch signaling pathway controls cellular interactions important for the specification of a variety of fates in both invertebrates and vertebrates. Key players in the Notch pathway are the TLE genes. TLEs associate with chromatin in live cells and specifically with Histone H3, but not with other core histones. Expression of the TLE genes, TLE1, TLE2, TLE3 and TLE4, correlate with immature epithelial cells that are progressing toward a terminally differentiated state, suggesting a role during epithelial differentiation.

TLE1 antibody can be used to differentiate synovial sarcoma from other sarcomas, including histologically similar tumors such as malignant peripheral nerve sheath tumor.

Synonyms: TLE1, anti-TLE1, anti TLE1, Enhancer of split groucho-like protein 1 (ESG1), Tle4l

Documentation

Specification Sheets

IVD - CE

Safety Data Sheets

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Product Details

Option	SKU	Price
Presentation: 3 ml Predilute	BSB-3794-3	$225.00
Presentation: 7 ml Predilute	BSB-3794-7	$337.00
Presentation: 15 ml Predilute	BSB-3794-15	$564.00
Presentation: .1 ml Concentrate	BSB-3794-01	$225.00
Presentation: .5 ml Concentrate	BSB-3794-05	$451.00
Presentation: 1 ml Concentrate	BSB-3794-1	$788.00
Presentation: Control Slides [5]	BSB-9412-CS	$101.00

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