TTF-1 (8G7G3/1), MMab
Price:
$145.00
SKU:
BSB 6001
Antibody type:
Mouse Monoclonal
Clone:
8G7G3/1
Isotype:
IgG1
Concentrate Dilution:
1:250-1:1000
Localization:
Nuclear
Tissue Control:
Lung, Thyroid, Adenocarcinoma of Lung
Species Reactivity:
Human, Dog
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Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Thyroid transcription factor-1 (TTF-1) is a protein that regulates transcription of genes specific to the thyroid, lung and diencephalon. It is also known as thyroid-specific enhancer binding protein and NKX-2. It is used as a marker to determine if a tumor oringinates in the lung or thyroid. TTF-1 positive cells are found in Type II pneumocytes and Clara cells in the lung. In the thyroid, follicular and parafollicular cells are positive.
TTF-1 antibody is useful in differentiating primary Adenocarcinoma of the Lung from Metastatic Carcinomas of the breast and Malignant Mesothelioma. It can also be used to differentiate Small- Cell Lung Carcinoma from lymphoid infiltrates. For lung cancers, Adenocarcinomas are usually positive, while Squamous Cell Carcinomas and Large Cell Carcinomas are rarely positive. Small-Cell Carcinomas (of any primary site) are usually positive.
Presentation
TTF-1 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: TTF 1, TTF1, NKX2-1, anti-TTF-1, anti TTF-1, anti-TTF 1, anti-TTF1, anti TTF 1, anti TTF1, Homeobox protein Nkx 2 1, NK2 homeobox 1, Nkx2 1, thyroid nuclear factor 1, Thyroid transcription factor 1, thyroid transcription factor 1 TTF 1 NK 2, Titf1
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 6001 | $145.00 |
| Presentation: 7 ml Predilute | BSB 6002 | $169.00 |
| Presentation: 15 ml Predilute | BSB 6003 | $321.00 |
| Presentation: .1 ml Concentrate | BSB 6004 | $179.00 |
| Presentation: .5 ml Concentrate | BSB 6005 | $368.00 |
| Presentation: 1 ml Concentrate | BSB 6006 | $645.00 |
| Presentation: Control Slides [5] | BSB 6007 | $77.05 |
