Tyrosinase (BSB-6), MMab
Price:
$201.00
SKU:
BSB 6008
Antibody type:
Mouse Monoclonal
Clone:
BSB-6
Isotype:
IgG2a
Concentrate Dilution:
1:50-1:200
Localization:
Cytoplasmic
Tissue Control:
Skin, Malignant Melanoma
Species Reactivity:
Human
Sharing Discount has been applied
Description
Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Tyrosinase is an enzyme that catalyzes the oxidation of phenols (such as tyrosine) and is widespread in plants and animals. Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. The gene for Tyrosinase is regulated by the Microphthalmia-associated transcription factor. A mutation in the tyrosinase gene leads to impaired tyrosinase production resulting in Type I Oculocutaneous Albinism, a hereditary disease that affects 1 in 17,000 people in the U.S.
Tyrosinase antibody has been found to be quite specific for melanotic lesions such as Malignant Melanoma and Melanotic Neurofibroma. Essentially no carcinomas express this marker.
Presentation
Tyrosinase antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: TYR, santi-Tyrosinase, anti Tyrosinase, anti-TYR, anti TYR, LB24 AB, Monophenol monooxygenase, OCA1A, OCAIA, SHEP3, SK29 AB, tumor rejection antigen AB, Tyrosinase, tyrosinase oculocutaneous albinism IA, Tyrosinase precursor, Albino locus protein, CMM8
Documentation
Specification Sheets
Safety Data Sheets
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Product Details
| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 6008 | $201.00 |
| Presentation: 7 ml Predilute | BSB 6009 | $368.00 |
| Presentation: 15 ml Predilute | BSB 6010 | $645.00 |
| Presentation: .1 ml Concentrate | BSB 6011 | $179.00 |
| Presentation: .5 ml Concentrate | BSB 6012 | $403.00 |
| Presentation: 1 ml Concentrate | BSB 6013 | $631.00 |
| Presentation: Control Slides [5] | BSB-9423-CS | $101.00 |
