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ace2 ace-2 anti-ace2 anti-ace-2 antibody immunohistochemistry ihc MAIN

ACE2 (BSB-135), MMab

Presentation:

Price: $229.00

SKU:	BSB-3702-3
Antibody type:	Mouse Monoclonal
Clone:	BSB-135
Isotype:	IgG1
Concentrate Dilution:	1:25-1:100
Localization:	Cytoplasmatic, Membranous
Tissue Control:	Kidney, Testis, Brain, Colon, Fallopian Tube
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Angiotensin Converting Enzyme 2 is a dipeptidyl carboxydipeptidase active in the renin-angiotensin pathway, which helps regulate cardiovascular and renal functions. ACE2 is a secreted protein that cleaves angiotensin I (AngI) into angiotensin 1-9, and angiotensin II (AngII) into vasodilator angiotensin 1-7. ACE2 is expressed in the heart and kidney, where it may counteract vasoconstriction by inactivating Ang II. It is also found in the GI tract, lungs, and testis, in endothelial cells and less in vascular smooth muscle cells. ACE2 can contribute to tumor inhibition by inactivating AngII, which has been found to participate in tumor proliferation, angiogenesis, and metastasis.

ACE2 has shown inhibitory effects on lung, prostate, breast, and liver cancer through various signaling mechanisms, and its expression may be correlated with immune cell penetration into the tissue. ACE2 also functions as the main receptor for the spike glycoprotein of human coronaviruses HCoV-NL63, SARS-CoV and SARS-CoV-2.

Presentation

ACE2 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: ace2, ace-2, ace 2, anti ace2, anti ace-2, anti-ace2, anti-ace-2, sars-cov-2 receptors, sars cov-2 receptors, covid-19 receptors, sars-cov-2 antibodies sars-cov-2 ihc, sars-cov-2 immunohistochemistry

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB-3702-3	$229.00
Presentation: 7 ml Predilute	BSB-3702-7	$418.00
Presentation: 15 ml Predilute	BSB-3702-15	$750.00
Presentation: .1 ml Concentrate	BSB-3702-01	$200.00
Presentation: .5 ml Concentrate	BSB-3702-05	$464.00
Presentation: 1 ml Concentrate	BSB-3702-1	$766.00
Presentation: Control Slides [5]	BSB-9002-CS	$154.00

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ACE2 (BSB-135), MMab

Intended Use

Summary and Explanation

Presentation

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