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Actin Muscle Specific (HHF35), MMab
| SKU: |
BSB 5022 |
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Antibody type:
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Mouse Monoclonal
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Clone:
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HHF35
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Isotype:
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IgG1/K
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Concentrate Dilution:
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1:50-1:200
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Localization:
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Cytoplasmic
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Tissue Control:
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Skeletal Muscle, Appendix, Prostate
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Species Reactivity:
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Human
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Actin is a globular-structural, 345 kDa protein that polymerizes in a helical fashion to form an actin filament (or microfilament). Actin filaments provide mechanical support for the cell, determine the cell shape, enable cell movements (through lamellipodia, filopodia, or pseudopodia); and participate in certain cell junctions, in cytoplasmic streaming and in contraction of the cell during cytokinesis. In muscle cells they play an essential role, along with myosin, in muscle contraction. In the cytosol, actin is predominantly bound to ATP, but can also bind to ADP. This antibody recognizes actin of skeletal, cardiac, and smooth-muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium.
Actin Muscle Specific Antibody recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are nonreactive. Neoplastic cells of non-muscle-derived tissue such as Carcinomas, Melanomas and Lymphomas are negative. This antibody is useful in the identification of rhabdoid cellular elements.
Presentation
Actin, Muscle Specific antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: actin, actin antibody, actin ihc antibody, actin ms, actin m.s., anti-actin, actin muscle-specific, ACT, ACTA3, ACTE, actin gamma 2 smooth muscle enteric, actin gamma enteric smooth muscle, actin like protein, ACTL3, ACTSG, alpha actin 3, Gamma 2 actin, smooth muscle gamma actin, loading control, loading controls, anti actin, muscle-specific
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3ml Predilute | BSB 5022 | $135.00 |
| Presentation: 7 ml Predilute | BSB 5023 | $166.00 |
| Presentation: 15 ml Predilute | BSB 5024 | $312.00 |
| Presentation: .1 ml Concentrate | BSB 5025 | $132.00 |
| Presentation: .5 ml Concentrate | BSB 5026 | $249.00 |
| Presentation: 1 ml Concentrate | BSB 5027 | $334.00 |
| Presentation: Control Slides [5] | BSB-9004-CS | $77.00 |
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