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Androgen Receptor (BSB-4), MMab

Presentation:

Price: $162.00

SKU:	BSB 6071
Antibody type:	Mouse Monoclonal
Clone:	BSB-4
Isotype:	IgG1
Concentrate Dilution:	1:100-1:500
Localization:	Nuclear
Tissue Control:	Prostate, Testis, Breast, Cervix
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

The androgen receptor (AR) is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone. The main function of the androgen receptor is as a DNA-binding transcription factor which regulates gene expression. However, the androgen receptor has additional functions independent of DNA binding. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and the brain.

Androgen Receptor antibody reacts with the androgen receptor and also with the newly-described A form of the receptor. This antibody does not cross-react with estrogen, progesterone or glucocorticoid receptors. Abnormalities in the AR-signaling pathway have been linked to a number of diseases, including Prostate Cancer, Kennedy’s Disease and male infertility.

Presentation

Androgen receptor antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: anti-androgen receptor, ar antibody, anti-ar, ar ihc, androgen-receptor, anti-androgen-receptor, anti androgen receptor

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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