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c-Myc (EP121), RMab
| SKU: |
BSB 6576 |
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Antibody type:
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Rabbit Monoclonal
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Clone:
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EP121
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Isotype:
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IgG
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Concentrate Dilution:
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1:10-1:50
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Localization:
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Nuclear, Cytoplasmic
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Tissue Control:
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Burkitt Lymphoma
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Species Reactivity:
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Human, Predicted: Mouse, Rat
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
Oncogene-encoded proteins c-Myc, n-Myc, and l-Myc function in cell proliferation, differentation and neoplastic disease. A mutated version of Myc is found in many cancers, which causes Myc to be constitutively expressed. This leads to the unregulated expression of many genes, some of which are involved in cell proliferation, and result in the formation of cancer. c-Myc is a transcription factor and is a proto-oncogene that is the focal point in cell cycle regulation, metabolism, apoptosis, differentiation, cell adhesion, and tumorigenesis.
A common human translocation involving Myc is t(8;14), which is criticial to the development of most cases of Burkitt’s Lymphoma. Malfunctions in Myc have also been found in carcinoma of the cervix, colon, breast, lung, and stomach.
Presentation
c-Myc antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: c Myc, MYC, cMyc, sc40, sc-40, 40, anti-c-Myc, anti c-Myc, anti-c Myc, anti-cMyc, anti c Myc, anti cMyc, anti-Myc, anti Myc, avian myelocytomatosis viral oncogene homolog, bHLHe39, Myc proto oncogene protein, transcription factor p64, v myc avian myelocytomatosis viral oncogene homolog, v myc myelocytomatosis viral oncogene homolog avian, class E basic helix loop helix protein 39, MRTL, myc related translation localization regulatory factor, Proto oncogene c Myc, 9E10
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 6576 | $290.00 |
| Presentation: 7 ml Predilute | BSB 6577 | $524.00 |
| Presentation: 15 ml Predilute | BSB 6578 | $572.00 |
| Presentation: .1 ml Concentrate | BSB 6579 | $322.00 |
| Presentation: .5 ml Concentrate | BSB 6580 | $709.00 |
| Presentation: 1 ml Concentrate | BSB 6581 | $1,083.00 |
| Presentation: Control Slides [5] | BSB-9040-CS | $77.00 |
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