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C4d (EP272), RMab

Presentation:

Price: $241.00

SKU:	BSB 2831
Antibody type:	Rabbit Monoclonal
Clone:	EP272
Isotype:	IgG
Concentrate Dilution:	1:100 / 1:50
Localization:	Cytoplasmic, Membranous
Tissue Control:	Tonsil, Lymph Node, Spleen, Kidney
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use.

This antibody is intended for use in Immunohistochemical (IHC) and Immunofluorescence (IF) applications on formalin-fixed paraffin-embedded tissues (FFPE), frozen tissue sections and cell preperations. Interpretation of results should be perfomed by a qualified medical professional.

Summary and Explanation

Complement component 4, or C4, plays a central role in the complement system. C4d is the final proteolytic remnant of deposited C4b on endothelium and remains covalently attached to endothelium for little more than a week. It is easily detectable by Immunohistochemistry. Anti-C4d combined with anti-C3d can be utilized as a tool for diagnosis of AR (Acute Rejection) and warrant prompt and aggressive anti-rejection treatment. C4d can be detected in peritubular capillaries in both chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival and is an aid in treating acute rejection.

Presentation

C4d is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Specification Sheets

IVD - CE

RUO

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Prediluted	BSB 2831	$241.00
Presentation: 7 ml Prediluted	BSB 2832	$438.00
Presentation: 15 ml Prediluted	BSB 2833	$789.00
Presentation: .1 ml Concentrated	BSB 2834	$134.00
Presentation: .5 ml Concentrated	BSB 2835	$359.00
Presentation: 1 ml Concentrated	BSB 2836	$700.00
Presentation: Control Slides [5]	BSB 2837	$63.00

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