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C4d (EP272), RMab
| SKU: |
BSB 2831 |
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Antibody type:
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Rabbit Monoclonal
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Clone:
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EP272
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Isotype:
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IgG
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Concentrate Dilution:
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1:100 / 1:50
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Localization:
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Cytoplasmic, Membranous
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Tissue Control:
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Tonsil, Lymph Node, Spleen, Kidney
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Species Reactivity:
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Human
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Intended Use
For In Vitro Diagnostic Use.
This antibody is intended for use in Immunohistochemical (IHC) and Immunofluorescence (IF) applications on formalin-fixed paraffin-embedded tissues (FFPE), frozen tissue sections and cell preperations. Interpretation of results should be perfomed by a qualified medical professional.
Summary and Explanation
Complement component 4, or C4, plays a central role in the complement system. C4d is the final proteolytic remnant of deposited C4b on endothelium and remains covalently attached to endothelium for little more than a week. It is easily detectable by Immunohistochemistry. Anti-C4d combined with anti-C3d can be utilized as a tool for diagnosis of AR (Acute Rejection) and warrant prompt and aggressive anti-rejection treatment. C4d can be detected in peritubular capillaries in both chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival and is an aid in treating acute rejection.
Presentation
C4d is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: C4b, C4a, C4, C4a anaphylatoxin, Complement C4 alpha chain, Complement C4 beta chain, Complement C4 gamma chain, complement C4 B, complement component 4 within H 2S, complement component 4B Childo blood group, Ss, complement component 4A Rodgers blood group, sex limited protein, Slp, complement component 4B Chido blood group, sex limited protein precursor, anti-c4d, anti c4d, antic4d
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 2831 | $285.00 |
| Presentation: 7 ml Predilute | BSB 2832 | $516.00 |
| Presentation: 15 ml Predilute | BSB 2833 | $932.00 |
| Presentation: .1 ml Concentrate | BSB 2834 | $158.00 |
| Presentation: .5 ml Concentrate | BSB 2835 | $423.00 |
| Presentation: 1 ml Concentrate | BSB 2836 | $827.00 |
| Presentation: Control Slides [5] | BSB-9045-CS | $77.00 |
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