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Caldesmon (BSB-19), MMab

Presentation:

Price: $151.00

SKU:	BSB 6099
Antibody type:	Mouse Monoclonal
Clone:	BSB-19
Isotype:	IgG1/K
Concentrate Dilution:	1:100-1:400
Localization:	Cytoplasmic
Tissue Control:	Appendix, Uterus, Breast Ducts
Species Reactivity:	Human

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Intended Use

For In Vitro Diagnostic Use

Summary and Explanation

Caldesmon antibody 1, also known as CALD1, is a human gene. Caldesmon is a calmodulin-binding protein. Like Calponin, Caldesmon tonically inhibits the ATPase activity of myosin in smooth muscle. This gene encodes a Calmodulin and actin-binding protein that play an essential role in the regulation of smooth muscle and nonmuscle contraction.

Two closely-related variants of human Caldesmon have been identified. The h-Caldesmon variant (120–150 kD) is predominantly expressed in smooth muscle, whereas I-Caldesmon (70–80 kD) is found in non-muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. Caldesmon antibody recognizes only the h-Caldesmon variant. Caldesmon antibody labels smooth muscle and tumors of smooth muscle, myofibroblastic, and myoepithelial differentiation. Anti-Caldesmon has also been used to differenti-ate Epithelioid Mesothelioma from Serous Papillary Carcinoma of the ovary.

Presentation

Caldesmon antibody (CALD-31) is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Synonyms: caldesmon bsb-19, anti-cald-1, anti-caldesmon 1,anti-caldesmon-1, CALD1, L Caldesmon, LCaldesmon, Caldesmon, caldesmon 1, CDM, H CAD, L CAD, MGC21352, NAG22, HCAD, LCAD

Specification Sheets

IVD - CE

Safety Data Sheets

SDS

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Option	SKU	Price
Presentation: 3 ml Predilute	BSB 6099	$151.00
Presentation: 7 ml Predilute	BSB 6100	$259.00
Presentation: 15 ml Predilute	BSB 6101	$494.00
Presentation: .1 ml Concentrate	BSB 6102	$119.00
Presentation: .5 ml Concentrate	BSB 6103	$451.00
Presentation: 1 ml Concentrate	BSB 6104	$624.00
Presentation: Control Slides [5]	BSB-9052-CS	$77.00