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CD57 (BSB-10), MMab
| SKU: |
BSB 5274 |
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Antibody type:
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Mouse Monoclonal
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Clone:
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BSB-10
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Isotype:
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IgG1/K
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Concentrate Dilution:
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1:100-1:500
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Localization:
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Membranous
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Tissue Control:
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Tonsil, Lymph Node, Spleen, Prostate
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Species Reactivity:
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Human, Dog, Cat
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
CD57 (NK-1) recognizes an oligosaccharide (MW 100-110 kDa) antigenic determinant on myeloid cells and on a variety of polypeptides, lipids and chondroitan sulfate proteoglycans. This surface antigen is associated with myelin-associated glycoprotein (MAG). The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.
Follicular Center-cell Lymphomas often contain many NK cells within the neoplastic follicles. CD57 antibody (NK-1) reportedly also reacts with a variety of cell types in non-lymphoid tissues. CD57 antibody stains neuroendocrine cells and their tumors, including Carcinoid Tumor and Medulloblastomas. CD57 also reacts with a variety of cell types in non-lymphoid tissues, including Neurofibroma, Ganglioneuroma, and Prostate Carcinoma.
Presentation
CD57 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: B3GAT1, anti-cd57, anti cd57, Beta 1 3 glucuronyltransferase 1, beta 1 3 glucuronyltransferase 1 glucuronosyltransferase P, CD57, CD57 antigen, Galactosylgalactosylxylosylprotein 3 beta glucuronosyltransferase 1, GlcAT P, GLCATP, GlcUAT P, Glucuronosyltransferase P, HNK 1, HNK1, LEU7, LEU7 antigen, NK 1, UDP GlcUA glycoprotein beta 1 3 glucuronyltransferase, GLCUATP, NK1, anti-nk1, anti nk1
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 5274 | $125.00 |
| Presentation: 7 ml Predilute | BSB 5275 | $188.00 |
| Presentation: 15 ml Predilute | BSB 5276 | $348.00 |
| Presentation: .1 ml Concentrate | BSB 5277 | $142.00 |
| Presentation: .5 ml Concentrate | BSB 5278 | $278.00 |
| Presentation: 1 ml Concentrate | BSB 5279 | $416.00 |
| Presentation: Control Slides [5] | BSB-9101-CS | $77.00 |
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