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CD68 (BSB-8), MMab
| SKU: |
BSB 5288 |
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Antibody type:
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Mouse Monoclonal
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Clone:
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BSB-8
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Isotype:
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IgG1
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Concentrate Dilution:
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1:250-1:1000
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Localization:
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Cytoplasmic, Membranous
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Tissue Control:
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Tonsil, Lymph Node
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Species Reactivity:
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Human, Mouse, Rabbit, Rat
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Intended Use
For In Vitro Diagnostic Use
Summary and Explanation
The CD68 antigen is a heavily glycosylated trans-membrane protein of 87-115 kDa which is specifically expressed by tissue macrophages, Langerhans cells and, at low levels, by dendritic cells. CD68 could play a role in phagocytic activities of tissuemacrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions.
CD68 antibody marks cells of monocyte/macrophage lineage. This antibody is capable of staining monocytes, Kupffer cells, osteoclasts, granulocytes and their precursors; Lymphomas are negative or show a few granules. This antibody may be useful for the identification of Myelomonocytic and Histiocytic Tumors. CD68 antibody may help to distinguish Malignant Fibrous Histiocytoma from other Pleomorphic Sarcomas.
However, since CD68 detects a formalin-resistant epitope that may be associated with lysosomal granules, other lysosome-rich cells may also produce positive results.
Presentation
CD68 antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Synonyms: CD68, Gp110, SCARD1, LAMP4, anti-CD68, anti CD68, anti-GP110, anti GP110, anti-LAMP4, anti LAMP4, anti-SCARD1, anti SCARD1, CD68 antigen, CD68 molecule, DKFZp686M18236, macrophage antigen CD68, macrosialin, scavenger receptor class D member 1
Specification Sheets
Safety Data Sheets
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| Option | SKU | Price |
| Presentation: 3 ml Predilute | BSB 5288 | $132.00 |
| Presentation: 7 ml Predilute | BSB 5289 | $155.00 |
| Presentation: 15 ml Predilute | BSB 5290 | $301.00 |
| Presentation: .1 ml Concentrate | BSB 5291 | $142.00 |
| Presentation: .5 ml Concentrate | BSB 5292 | $256.00 |
| Presentation: 1 ml Concentrate | BSB 5293 | $451.00 |
| Presentation: Control Slides [5] | BSB-9105-CS | $77.00 |
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